ABSTRACT
Objective To explore the distribution of syndromes and the characteristics of damp-induced disease in patients with multiple sclerosis in Lingnan area,and to improve the reference for TCM treatment of MS patients.Methods A retrospective analysis of the general information of 268 patients with multiple sclerosis (MS) admitted to our hospital from March 2015 to 2016 was conducted.And the information on four diagnoses of Chinese medicine,including the main manifestations,tongue pulse,frequency were for the cluster analysis.The Multivariate logistic regression analysis was used to analyze the factors influencing MS syndromes.The distribution and dynamic changes of the symptoms of the patients at the initial diagnosis,4 weeks after treatment and 8 weeks after treatment were observed,and the dynamic changes of the syndrome form were analyzed.Results In the course of the development of MS patients,the sigle syndrome and 6 syndromes can appear simultaneously.Among them,there were syndrome of the wind,wet,phlegm,heat and blood stasis.At the 4 and 8 weeks after treatment,2nd syndromes gradually increased,but the 3rd syndromes and 4th syndromes remain unchanged,and the 5th syndrome significantly decreased.The syndrome is complicated and changeable from the side of the development process.The results of multi factor Logistic regression analysis showed that purple tongue was an important factor of blood stasis [OR (95％ CI)=2.357(1.996-3.017)],and the yellow greasy coating was an important factor of hot dampness [OR (95％ CI)=3.654(3.125-4.876)],and the thin and weak pulse was the important factor of the deficiency of liver and kidney[OR (95％ CI)=3.983(2.349-4.218)];deficiency pulse was an important factor affecting Qi and blood deficiency syndrome[OR (95％ CI)=2.852(2.068-3.192)];limb twitching was an important factor affecting kidney yang deficiency syndrome [OR (95％ CI)=3.850(1.037-16.524)],and the above data were statistically significant (P＜0.05).For patients with damp heat attacking vesselssyndrome,the most frequent clinical symptoms were the spinal sensory disorders,cranial nerve disorders and cerebellar symptoms,emotional disorders and mental disorders,consciousness disorders and epilepsy,two bowel movements and weakness.Conclusions The wind,wet,phlegm,heat and blood stasis of the MS patients in south of the Five Ridges gradually increase.With the treatment,the syndrome combination was gradually simplified,the essential contradiction gradually revealed,the single syndrome gradually merged,the 2 syndrome gradually increased,the 3 syndrome and the 4 syndrome remained constant.
ABSTRACT
Diabetic diarrhea is one of the chronic complications of diabetes, which is particularly closely related to the spleen and kidney. Using these two organs as the theoretical foundation, the root of diabetic diarrhea can be grasped. Pathogenic dampness is responsible throughout the whole process of diabetic diarrhea. Using syndrome differentiation, deficiency is as the basic pattern and excess is the syndrome for diabetic diarrhea; diagnosis and treatment combine symptoms and syndromes, which not only particularly pay attention to protecting the spleen and kidney, but also clearing pathogenic dampness. At the same time, flexible medication is applied according to dynamic symptoms, which can achieve good efficacy.
ABSTRACT
After reading and analyzing Shi Re Bing Pian,Xue Shengbai's methods of dampness-eliminating in damp-heat diseases,such as ventilating dampness,resolving dampness,drying dampness and removing dampness,were discovered.The way he establishing therapeutic methods has great instructional meaning in clinical treatment of traditional Chinese medicine.